MetaOrtho Blog
Evidence-based articles from a board-certified orthopedic surgeon on monitoring and supporting your bones, muscles, and joints during GLP-1 weight loss.
Two major studies at the AAOS 2026 Annual Meeting link GLP-1 medications to 29% higher osteoporosis risk, 2.55x osteomalacia increase, and ~50% higher tendon rupture risk — often during everyday activities like reaching forward.
A meaningful share of the weight lost on GLP-1 drugs is lean mass — muscle, bone, and connective tissue. Two AAOS 2026 studies put hard numbers on the bone, gout, and tendon-rupture cost. Here's what to do about it.
Two major studies presented at the 2026 AAOS Annual Meeting found GLP-1 users face a 29% higher osteoporosis risk, a 2.55x higher osteomalacia risk, and a ~50% higher tendon-rupture risk versus matched controls. Here's what it means for you.
Rapid weight loss on Ozempic, Wegovy, or Mounjaro can spike your uric acid levels and trigger painful gout attacks. Here's the science behind the connection and how to reduce your risk.